What Is Paxlovid Rebound And How Common Is It? , #Paxlovid #rebound #common Welcome to OLASMEDIA TV NEWSThis is what we have for you today:
President Joe Biden tested positive for Covid-19 for the second time on Saturday, nine days after his original diagnosis and just days after he tested negative.
The president’s physician, Dr. Kevin O’Connor, said the most recent infection was due to “rebound COVID positivity” as a result of treatment with the drug Paxlovid.
So what is Pavloxid rebound?
A series of studies have shown that people with COVID-19 can remain contagious into their second week with the virus after initially experiencing symptoms.
Yonatan Grad, an infectious disease specialist at the Harvard TH Chan School of Public Health, said: Nature that ten days is a good rule when people are no longer allowed to be contagious.
But he added that a small number could be contagious after 10 days, with some of those cases linked to the use of the antiviral drug Paxlovid.
“There is a rebound phenomenon where people will see their symptoms seem to go away and they may even test negative on a rapid test, but a few days later the symptoms and the virus come back,” he said. Nature.
In a July 30 memo, the physician wrote to the president, Dr. O’Connor, that “as described last week, the president acknowledged that a potential for so-called ‘rebound’ COVID positivity was seen in a small percentage of patients treated with PAXLOVID. as to ensure early detection of any recurrence of viral replication”.
“After testing negative on Tuesday night, Wednesday morning, Thursday morning and Friday morning, the president tested positive late Saturday night with antigen testing. This actually represents ‘rebound’ positivity,” added Dr O’Connor.
“Folks, today I tested positive for COVID again,” Mr Biden tweeted at 2:45 p.m. on Saturday. “This happens to a small minority of people. I have no symptoms but I am going to isolate for the safety of everyone around me. I’m still at work and will be back on the road soon.”
“The president has not experienced any renewed symptoms and is still feeling quite well,” Dr O’Connor added. “If this is the case, there is no reason to restart treatment at this time, but we will obviously continue to monitor closely.”
Infectious disease specialist at Massachusetts General Hospital, Amy Barczak, told: Nature that “it is very unusual for people to remain contagious after ten days”.
Mr Biden first tested positive on July 21 – nine days ago.
dr. Barczak adds: Nature that “antivirals change the dynamics of symptoms, change the dynamics of the immune response, and change the dynamics of how you shed the virus.”
“I think this is very important because after ten days in the world people think they are not contagious. But if they have Paxlovid rebound, maybe they are,” she added.
In a health advisory from the Centers for Disease Control and Prevention on May 24the agency said that “Paxlovid is still recommended for early-stage treatment of mild to moderate Covid-19 in individuals at high risk of progression to serious illness” and that the “treatment will help prevent hospitalization and death.”
“Covid-19 rebound has been reported to occur between two and eight days after the initial recovery and is characterized by a recurrence of Covid-19 symptoms or a new positive viral test after testing negative,” the agency added. . “A brief return of symptoms may be part of the natural history of… the virus that causes COVID-19… in some individuals, regardless of Paxlovid treatment and regardless of vaccination status.”
The agency also said that “limited information currently available from case reports suggests that individuals treated with Paxlovid experiencing Covid-19 rebound have had mild illness; there are no reports of serious illness”, adding that “there is currently no evidence that additional treatment with Paxlovid or other… therapies is needed in cases where a Covid-19 rebound is suspected”.