The men landed on a beach in the village of Gambell on St Lawrence Island after crossing the Bering Sea and requested asylum.
A spokesman for the Department of Homeland Security said the couple’s claim is currently pending.
Thousands have fled Russia to avoid being enlisted in President Vladimir Putin’s war against Ukraine.
Gambell – home to fewer than 500 residents – is located on the northwestern cape of St. Lawrence Island and 56 miles from Russia’s Chukchi Peninsula.
It is closer to Russia than to mainland Alaska.
According to local media, residents of Gambell can see the Russian territory of Siberia across the sea.
A local town clerk told KTUU news station that the men had sailed there from the northeast Russian town of Egvekinot, traveling about 300 miles by sea, and have since flown off the island.
DHS said the men came ashore in a small boat on Tuesday and flew to Anchorage, Alaska’s largest city, for vetting and screening.
At a news conference on Wednesday, Alaska Governor Mike Dunleavy said their arrival was a surprise.
He added: “We do not expect a continuous flow of individuals or a fleet of individuals.
“We have no indication that this is going to happen, so this could be a one-off.”
Senator Dan Sullivan said community leaders in Gambell had contacted him about the men’s arrival.
Sullivan said he urged federal authorities to have a plan ready in case more Russians flee to Alaskan Bering Strait communities.
Ukrainian soldiers sit on an armored vehicle as they drive between Izium and Lyman in Ukraine (Francisco Seco/AP)
/ APHe wrote in a statement on Thursday: “This incident makes two things clear: First, the Russian people do not want to wage Putin’s war of aggression against Ukraine.
“Second, given Alaska’s proximity to Russia, our state plays a vital role in ensuring America’s national security.”
His fellow Senator Lisa Murkowski said the incident underscores the need for a stronger security posture in America’s Arctic.
Both have pushed for the expansion of strategic defense capabilities and infrastructure in the state to combat the threats Russia poses to the region.
Citing a Kremlin source, a Forbes Russia report this week claimed as many as 700,000 men have left the country since Putin announced a partial troop mobilization on Sept. 21.
The mass exodus comes as Russian troops have suffered heavy casualties and morale crushing defeats on the battlefield.
But while most of the men have fled overland to neighboring Kazakhstan, Georgia and Finland, as well as other European countries, the arrival in Alaska is a first.
In August, US authorities stopped Russians without legal status who attempted to enter from Canada 42 times. That was more than 15 in July and nine times in August 2021.
Russians are more likely to try to enter America through Mexico, which does not require a visa.